Dwayne Smith has been called up as replacement for Chris Gayle for the four matches.
Gayle experienced stiffness in his lower back following the first T20 International against Ireland on Wednesday. He did not play in the second T20 International on Friday. He had precautionary scans and will have medical management and necessary treatment in Jamaica.
Smith was the highest runscorer and MVP in the recent domestic Super50 tournament in Trinidad & Tobago. He made 232 runs in four innings at an average of 58 runs per innings to help Barbados win the Clive Lloyd Trophy.
The West Indies will face Ireland on a one-off ODI on Sunday at Sabina Park. They travel to Antigua on Monday for three ODIs at the Sir Vivian Richards Cricket Ground.
SQUAD v IRELAND
Dwayne Bravo (Captain)
SQUAD v ENGLAND
Dwayne Bravo (captain)
Ottis Gibson (Head Coach)
Richie Richardson (Team Operations Manager)
Stuart Williams (Assistant Coach)
Andre Coley (Assistant Coach)
Saqlain Mushtaq (Assistant Coach)
C.J. Clark (Physiotherapist)
Hector Martinez Charles (Strength & Conditioning Coordinator)
Richard Berridge (Video & Statistical Analyst)
Virgil Browne (Massage Therapist)
Philip Spooner (Media Relations Manager)