Two players from South Africa's tour of England are returning home and are in doubt for Birmingham 2022.
After missing the first T20I, Marizanne Kapp and Tumi Sekhukhune will miss the remainder of the series and are in doubt for the Games, which begin on July 29.
Sekhukhune re-injured her groin earlier on tour and will recuperate at home, while Kapp returns to Gqeberha to attend a family matter.
While a Cricket South Africa statement did not disclose the matter, Kapp's wife and Proteas teammate Dane van Niekerk confirmed via social media that their brother-in-law had been involved in an accident that had left him in intensive care.
Batter Tazmin Brits was called to the squad for the rest of the T20I series, though a final Commonwealth Games squad is yet to be determined, and must go through the South African Sports Confederation and Olympic Committee as per Games requirements.
With Kapp and Sekhukhune unlikely to return, it leaves South Africa at risk of missing out on a medal at the Games, having already lost Lizelle Lee (retired from international cricket) and van Niekerk, who is still nursing an ankle injury side-lined her before the ICC Women's Cricket World Cup earlier in the year.
South Africa's campaign begins on July 30 against New Zealand at Edgbaston, with Sri Lanka and the tournament hosts also making up Group B.

THIS IS THE BIG TIME!
Feel the buzz in the stands and see the best teams in the world play on the biggest stage of all.
Trending News
-
1
1 Michael Neser replaces Josh Hazlewood in Australia's World Test Championship Final squad
Injury has caused Australia to make a late change to their 15-player squad for this week's ICC World Test Championship clash against India at The Oval, with experienced seamer Josh Hazlewood ruled out of the match due to his ongoing Achilles and side issue.
-
2 Jack Leach ruled out of Ashes in huge blow for England
-
3 The stunning stats as Steve Smith underlines his batting brilliance
-
4 India and Australia kits unveiled for World Test Championship Final
-
5 Experienced opener added to West Indies squad for Cricket World Cup Qualifier